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In PCOS, miRNAs modulate critical processes such as steroid hormone synthesis [84], follicular development and maturation (94), fatogenesis (95), and insulin signaling pathways (96)

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Transformation and transfection assays with win-treated plasmid DNA revealed that the DNA lesions caused by win have serious biological consequences and may interfere with DNA transcription, replication and repair resulting in replication block, mutagenesis, apoptosis and cell death